Positions Available

All faculty in Pediatrics, Medical Genetics and Obstetrics & Gynecology are able to take MatCH students. Listed below are faculty who have specifically stated availability in their laboratories, but students are encouraged to contact any faculty member in these departments whose research is of interest to them.

Medical Genetics

Fred Berry (fberry@ualberta.ca)

Department: Medical Genetics
Degree: MSc or PhD (MSc Possibly transferring to a PhD)
Project Title: Genetic regulation of skeletal growth and patterning
Keywords: Gene regulations, Bone, Development
Name of Supervisor: Dr Fred Berry
Proposed start date: January 2014

Oana Caluseriu (caluseri@ualberta.ca)

Department: Medical Genetics
Degree: MSc
Project Title: Molecular characterization of gens causing rare disorders in children
Keywords: Rare diseases, Craniofacial anomalies, Limb anomalies
Name of Supervisor: Dr Oana Caluseriu
Proposed start date: January 2014

Daniel Graf (dgraf@ualberta.ca)

Department: Medical Genetics
Degree: MSc or PhD
Project Title: Bmp7 function in cranial neural crest cells: molecular and cellular characterization of a complex craniofacial phenotype
Keywords: bone morphogenetic proteins, mouse genetics, craniofacial development, craniofacial malformation, neural crest cells, bone formation,
Name of Supervisor: Dr. Daniel Graf
Proposed start date: Flexible

For more information: www.dentistry.ualberta.ca/en/AboutUs/.../DanielGraf.aspx


Sarah Hughes (shughes1@ualberta.ca)

Department: Medical Genetics
Degree: MSc or PhD
Project Title: A genetic model for Neurofibromatosis Type II: Identification and characterization of protein partners of the Merlin tumour suppressor protein
Keywords: Drosophila, tumour suppressor, cell adhesion, cytoskeleton
Name of Supervisor: Sarah Hughes
Proposed start date: Flexible

For more information: http://www.medgen.ualberta.ca/AboutUs/Faculty/SarahHughes.aspx

Ordan Lehmann (ordan.lehmann@ualberta.ca )

Department: Medical Genetics
Degree: MSc or PhD
Project Title: Developing mechanistic insight into neurogenetic disease
Keywords: Neurogenetics, eye disease, stroke, vascular biology
Name of Supervisor: Ordan Lehmann
Proposed start date: Flexible

Zhixiang Wang (zwang@ualberta.ca)

Department: Medical Genetics
Degree: MSc or PhD
Project Title: Overcoming the drug-resistance in breast cancer by understanding the mechanisms and designing novel treatment strategies.
Name of Supervisor: Dr Zhixiang Wang
Proposed start date: Flexible

For more information: http://www.medgen.ualberta.ca/AboutUs/Faculty/ZhixiangWang.aspx

Rachel Wevrick (Rachel.wevrick@ualberta.ca)

Department: Medical Genetics
Keywords:  Medical Genetics, Neuroscience, Obesity, Development, Cell Biology, Gene regulation
Brief Project Description:  Two positions are available for students with a B.Sc in Biology, Life Sciences or a related discipline, and a keen interest to learn.  The projects examine differences in gene expression, morphology, cell biology, and physiology in knock-out mouse models of Prader-Willi syndrome. Techniques will include cell biology, neurophysiology, RNA in situ hybridization, and immunohistochemistry.
Name of Supervisor: Dr. Rachel Wevrick
Proposed start date:  Winter 2015 or Fall 2015

For more information: http://www.medgen.ualberta.ca/en/AboutUs/Faculty/RachelWevrick.aspx 

Toshifumi Yokota (toshifumi.yokota@ualberta.ca)

Department: Medical Genetics
Degree: MSc (with possibility of transfer to PhD)
Project Title: Muscular Dystrophy, Antisense Therapy, Muscle Membrane Imaging
Keywords:  Our laboratory is working towards the goal of finding cures for muscular dystrophies and neuromuscular disorders. 
Name of Supervisor: Toshifumi Yokota
Proposed start date: Flexible
Project examples:

1. Antisense and exon skipping therapy
Antisense therapy is an approach to fighting diseases using DNA-like molecules.  We aim to expand the applicability of antisense therapy and rescue various forms of muscular dystrophies and neuromuscular disorders.

2. Revertant Fibre Analysis
Duchenne muscular dystrophy (DMD) is among the most common lethal genetic disorders caused by a lack of dystrophin. Interestingly, most dystrophic muscles show a small proportion of dystrophin positive fibres called revertant fibres. Our current projects involve molecular analysis of revertant fibres. Results from this study may identify novel biomarkers and potential targets for DMD treatment.

For more information: http://www.medgen.ualberta.ca/AboutUs/Faculty/ToshifumiYokota.aspx

Obstetrics & Gynecology

Sandy Davidge (sandra.davidge@ualberta.ca)

Department: Obstetrics and Gynecology
Degree: PhD
Project TitlePregnancy complications and maternal and fetal outcomes
Keywordspreeclampsia, fetal growth restriction, vascular function
Name of Supervisor: Sandy Davidge
Proposed start date: Flexible start time

For more information:  http://obgyn.med.ualberta.ca/AboutUs/Academic%20Faculty/Pages/default.aspx?P=5

Denise Hemmings (denise.hemmings@ualberta.ca) - 2 sample projects

Department: Obstetrics and Gynecology
Degree: MSc (with possibility of transfer to PhD)
Project Title: A new mechanism for control of vascular tone by regulation of endothelial permeability in human resistance arteries: is this dysfunctional in pregnancy complications?
Keywords: Preeclampsia, vascular function, sphingosine 1-phosphate
Name of Supervisor: Denise Hemmings
Proposed start date: January 2015 

Department: Obstetrics and Gynecology
Degree: MSc (with possibility of transfer to PhD)
Project Title: The impact of pregnancy hormones on vascular responses to sphingosine 1-phosphate, a bioactive lipid. 
Keywords: Pregnancy hormones, vascular responses, endothelium
Name of Supervisor: Denise Hemmings
Proposed start date: January 2015

Pediatrics


Dr Stephane B Bourque (sbourque@ualberta.ca)

Department:  Pediatrics
Degree:  MSc of Phd
Project Title:  Prenatal resveratrol as a therapeutic for fetal iron deficiency anemia
Key words:  Iron deficiency anemia, fetal programming, kidney, blood vessels, resveratrol
Name of Supervisor:  Stephane Bourque
Proposed Start Date:  Flexible
For more information on our research program:  http://www.pmcol.ualberta.ca/people/Faculty/BourqueDetail

Dr Shairaz Baksh (sbaksh@ualberta.ca  (2 Sample projects)

Department:
 Pediatrics
Degree: MSc or PhD
Project Title: Molecular link between inflammation and cancer
Keywords: inflammation, colorectal cancer, inflammatory bowel disease
Name of Supervisor: Shairaz Baksh
Proposed Start Date: Flexible 

Department: Pediatrics
Degree: MSc or PhD
Project Title: E3 ligase regulation of Cancer: Molecular influence of the RASSF1A/MOAP-1 tumour suppressor Pathway. 
Keywords: tumor suppressor protein, leukemia, miRNA
Name of Supervisor: Shairaz Baksh
Proposed start date:  Flexible

Geoff Ball (geoff.ball@ualberta.ca)

Department: Pediatrics
Degree: MSc or PhD
Project Title: Preventing and managing pediatric obesity
Keywords: Obesity, Family, Communication, Motivation, Qualitative, Quantitative, Interventions
Name of Supervisor: Geoff Ball
Proposed Start Date: Flexible

For more information: http://childhoodobesityresearchinsight.wordpress.com/

Francois Bolduc (fbolduc@ualberta.ca)

Department: Pediatrics
Degree: Msc, PhD
Project Title: Neurogenetics of intellectual disability and memory. 
Keywords: We use various techniques to understand the genetic basis of intellectual disability in children. This includes, comparative genomic hybridization, DNA sequencing and comprehensive neuro-cognitive investigations. We then use animal models, including Drosophila, to understand how these genes function normally and get disrupted in disease to lead to the learning and cognitive defects seen in the patients.  Our goal is to develop treatment to improve the functioning of patients with intellectual disability.
Name of Supervisor: Francois Bolduc
Proposed Start Date: Flexible

Andrea Haqq (andrea.haqq@albertahealthservices.ca )

Department: Pediatrics
Degree: MSc
Project Title: ANS function and metabolic profiling of children with Prader-Willi Syndrome
Keywords: childhood obesity, autonomic nervous system, metabolism, Prader-Willi Syndrome
Name of Supervisor: Dr Andrea Haqq
Proposed start date: Fall 2015 or Winter 2016
A student with an academic background in neurology, physiology or is kinesiology preferred

For more information: http://www.adi.ualberta.ca/en/Research%20Members/ADIResearchersinLiKaShing/AndreaHaqq.aspx

Lisa Hartling (hartling@ualberta.ca)

Department: Pediatrics
Degree: MSc or PhD
Project Title: multiple projects in systematic reviews, evidence synthesis, randomized trials, methodological research, child health
Keywords: systematic reviews, methodological research, child health
Name of Supervisor: Lisa Hartling
Proposed start date: Flexible

Anita Kozyrskyj (kozyrsky@ualberta.ca)

Department: Pediatrics
Degree: MSc or PhD
Project Title: The impact of maternal overweight and other perinatal factors on the infant gut microbiome
Keywords: infant microbiome overweight
Name of Supervisor: Anita Kozyrskyj
Proposed start date: 2015

Richard Lehner (richard.lehner@ualberta.ca

Department: Pediatrics   
Degree: MSc or PhD
Project Title: Obesity, diabetes and fatty liver disease. Descriptions: We are investigating how mutations in certain proteins either protect from or lead to fatty liver disease, obesity and cardiovascular disease.
Keywords: lipid metabolism
Name of Supervisor: Richard Lehner
Proposed start date: Sept 2015

For more information: http://www.mcbl.ca/ and http://www.ualberta.ca/CELLBIOLOGY/

Joanna MacLean (maclean5@ualberta.ca) - 2 projects

Department: Pediatrics   
Degree: MSc
Project Title: Cardio-respiratory function in a mouse model of sickle cell disease
Keywords: pulmonary function, animal, hematological disease
Name of Supervisor: Joanna MacLean/John Greer
Proposed start date: September 2014

Department: Pediatrics
Degree: MSc or PhD
Project Title: Long term cardio-respiratory outcomes of infants admitted to the NICU
Keywords: Pre-term infants, longitudinal study, epidemiology
Name of Supervisor: Joanna MacLean
Proposed start date: September 2014

Lesley Mitchell (Lesley.mitchell@ualberta.ca)

Department: Pediatrics
Degree: MSc possibly continuing to a PhD
Project Title: Relationship of prothrombotic markers in determining risk of thrombosis in children with cancer
Keywords: genetics, clinical translational, pediatric cancer
Name of Supervisor: Lesley Mitchell
Proposed start date:  2015

Sujata Persad (sujata.persad@med.ualberta.ca)

Department: Pediatrics
Degree: MSc
Project Title: Understanding the molecular mechanisms of cancer progression.
Keywords: Epithelial to mesenchymal transition, Metastasis, Intracellular Signaling
Proposed start date: Flexible

Richard Schulz (richard.shulz@ualberta.ca)

Department:  Pediatrics
Degree: MSc or PhD
Project Title:  Matrix metalloproteinases in heart and vascular diseases, from bench to bedside. Projects include those from basic science to translational and clinical research.
Keywords: Ischemic heart disease, heart failure, cardiomyopathy, sepsis, Chagas disease
Name of Supervisor:  Richard Schulz
Proposed start date:  Flexible

For more information: http://www.pmcol.ualberta.ca/people/faculty/SchulzDetail.html

Alvaro R. Osornio Vargas (osornio@ualberta.ca)

Department: Pediatrics
Degree: MSc and PhD
Project Title: Air pollution and adverse birth outcomes
Keywords: prematurity, small for gestational age, industrial pollutants, urban air pollution
Name of Supervisor: Alvaro R. Osornio Vargas
Proposed start date:  Flexible 

For more information: http://www.ualberta.ca/~osornio/index.html

Dawei Zhang (dzhang@ualberta.ca)

Department: Pediatrics
Degree: MSc and PhD
Project Title: How PCSK9 promotes the degradation of the LDL receptor and reduces plasma levels of LDL
Keywords: High density lipoprotein, low density lipoprotein, LDL receptor, PCSK9, ATP-binding cassette transporter
Name of Supervisor: Dawei Zhang
Proposed start date:  Flexible